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Ventricular septal defect, atrial septal defect, tetralogy of Fallot, coarctation of the aorta, or cardiac rhythm dysfunction

Another benefit of saffron supplementation is improved objective sleep quality

However, it is not recommended for patients who: (i) have an overvaluation of shape and weight, (ii) a history of anorexia nervosa or bulimia nervosa, or (iii) are experiencing major depression or other severe, unstable mental health disorders

The meta-analysis then calculated any differences in effects on HbA1c (glycated haemoglobin, a measure of blood sugar control), body weight, and also the risk of adverse events

Risk of irritation or allergic reaction, especially with aggressive ingredients

After 40, more volume creates more cortisol, more water retention, and more stall