This cardiomyopathy is characterized by dysfunction of cardiac mitochondria, a decrease in plasma selenium, decreased cardiac GPx1 expression, increased oxidative stress in the myocardium as reflected by an increase in 8-hydroxy-2-deoxy-guanosine content of nuclei, and decreased whole blood GPx1 activity [24, 25]
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Blood tests can help determine if the current dosage is adequate or if adjustments are needed
Luxin Li, [email protected] This article was submitted to Molecular Diagnostics and Therapeutics, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
