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Methods: AIR recombination reads were recovered from primary tumor sample whole exome sequences (WXS) and RNA sequences (RNAseq) of 377 HCC cases in The Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC) dataset and WXS of 89 HCC cases in the Human Genome Sequencing Center at Baylor College of Medicine (HGSC-BCM) HCC dataset

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Tutwiler V, Mukhitov AR, Peshkova AD, Le Minh G, Khismatullin RR, Vicksman J, et al

Salehi B, Berkay Ylmaz Y, Antika G, et al

Prior reports are limited by small population size and inadequate phenotyping for the identification of cirrhosis