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Evidence from preclinical and clinical studies supports the notion that regular consumption of polyphenol-rich foods correlates with attenuated hepatic inflammation and a reduced likelihood of disease progression to more severe forms, including steatohepatitis

Therefore, the design of combination regimens must be informed not only by the metabolic crosstalk (e.g., via GSH depletion) but also by real-time immune monitoring of the TME

PLoS ONE 10(11):e0143344

It works by training the immune system

Annu Rev Pharmacol Toxicol 38: 97120

User experiences and clinical understanding suggest several possible contributing factors