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Identification of two missense mutations in the GIP receptor gene: a functional study and association analysis with NIDDM: no evidence of association with Japanese NIDDM subjects

Pfizer is adding to its cardiometabolic pipeline with a new, glucagon-like peptide 1 (GLP-1) receptor agonist-focused license agreement, worth up to $1.935 billion

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Nonetheless, these probes can be further developed to investigate the impact of gene mutations on glutamate receptors in animal models of autism

Once inside, it inhibits NF-kB and MAPK cascades, preventing production of pro-inflammatory cytokines at the transcriptional level