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Participants applied GHK-Cu cream twice daily

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Cell Mol Life Sci 70:17531761 Halliday MR, Pomara N, Sagare AP, Mack WJ, Frangione B, Zlokovic BV (2013) Relationship between cyclophilin A levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers and blood-brain barrier breakdown

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F 1.8,7.2 = 38.24, p = 0.0002 using Baseline control

Intriguingly, we observed a 30% increase in glycolysis and a 33% increase in mitochondrial glucose oxidation in MTP siRNA versus control siRNAtreated cells (ECAR: 6.2 0.1 vs