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Furthermore, high CHAC1 expression was associated with poor prognosis in sarcoma patients, indicating its potential role in RMS tumorigenesis and as a therapeutic target ( 7.2 Pharmacotherapeutic targeting of CHAC1 The therapeutic targeting of CHAC1 has been extensively studied across various cancer types using a wide array of medications (summarized in Table 4)

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Chemical reactions that break the peptide chain, particularly hydrolysis, accelerate

Mechanistically, disulfide bonds resist reductive cleavage in circulation by being embedded in the linker