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Important Considerations for Patients Who Have Undergone Metabolic or Bariatric Surgery Patients who have had metabolic or bariatric surgery should have a separate and specific discussion before starting a GLP 1 receptor agonist as part of Obesity Management Medication therapy

Essentially, as the weeks pass, appetite and blood sugar regulation can become worse, and some people can experience weight fluctuations or realize that they are hungrier more, unless another strategy is employed

Another study where five times lower doses were used also showed significant improvement in the course of Retinitis pigmentosa , Figure 3 [20]

This reduces early discomfort

The remaining users experienced temporary worsening that resolved with dose adjustment or brief medication pause