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Work on thymalin commonly focuses on thymic peptide mixtures rather than a single defined amino-acid sequence

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Results: The expression of MMPs and various apoptotic markers are down-regulated following administration of IGF-1 in a dose-dependent fashion while significantly up-regulation of TIMP-1

These results suggested that alveolar cell lineage plasticity was upregulated and AT2 or PAPCs played a positive role in differentiation into AT1 cells during the lung recovery

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