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Finally, there has been a growing interest in cellular signaling mechanisms altered by acute and chronic exposure to LCACs and Ca 2+ overload mediated by the acylcarnitines [reviewed by Rutkowsky et al., 2014

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This patient-centric approach did contribute to complexity when interpreting comparisons to placebo at the 52-week time point

In the UK, NICE technology appraisal TA875 (Semaglutide for managing overweight and obesity, 2023) outlines the approved use of semaglutide 2.4 mg (Wegovy) for weight management within specialist NHS weight management services

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