Many people feel early fatigue from smaller meals or mild nausea, then notice steadier days as glucose variability declines
It has been described that semaglutide, liraglutide, exendin-4, NLY01, and the GLP-1/GIP dual receptors agonist (DA-JC1, DA-JC4, DA5-CH, and DA3-CH), enclose neuroprotective properties in the MPTP mouse and the 6-hydroxydopamine (6-OHDA)-lesion induced rat models (Cao et al., 2016
Clinical trials have shown that GLP-1R agonists increase microvascular blood volume and flow in cardiac muscle, and these effects are preserved in obese individuals with vascular insulin resistance
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Copper overload, similar to iron overload, leads to impaired cell function and eventually cell death
That is meaningfully higher than what we see with todays GLP-1 and dual agonist options