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The effective blood-brain barrier mechanism impeding the transport of monoamines has been attributed to both the presence of tight junctions cementing adjacent endothelial cells of the cerebral capillary walls, along with high concentrations of dopa decarboxylase and monoamine oxidase (MAO) in the cerebral capillary endothelium (Bertler et al, 1966

Common research protocols cited in the peptide community use 1 to 2 mg, 3 to 5 times weekly, over 8 to 12-week cycles

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Anat Rec 119, 1133

Bantle 2009