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doi: 10.1038/nrurol.2017.98 12 MottolaFPalmieriICarannanteMBarrettaARoychoudhurySRoccoL

Vibha Singhal, a pediatric obesity specialist at UCLA, emphasize that while these medications can lead to significant weight loss and improved health in teens, long-term effects, especially in younger children, are still unknown

26 Clinical data on GLP-1 receptor agonists and pancreatitis occurrence Postlethwaite, et al 7 reported that, among 2,245 patients with obesity (mean body mass index 39.7 kg/m2 ) who started GLP-1 receptor agonist therapy, 49 (2.2%) developed acute pancreatitis

Importantly, these results suggest tirzepatides benefits extend beyond glycemic control, addressing inflammation, congestion, and metabolic loadall major drivers of HFpEF

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Regular monitoring ensures progress is tracked, and treatment plans are adjusted to achieve the best results