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The strongest human evidence is topical, including the Leyden 2002 photoaging trial and a 2023 IRB-approved 21-woman topical NEEL gel study reporting an average 28% increase in skin collagen density at 3 months

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Shah et al

The logical identification of S 1 and S 2 building blocks led to the discovery of effective DPP-2 inhibitors, which were characterized by their high selectivity for DPP-2 over DPP-4

L-Carnitine picks up that fat and carries it to where your body burns it as energy so it doesn't go back