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High glucose levels (hyperglycemia) and increased glucose metabolites have been shown to activate hepatic expression of ChREBP, resulting in the upregulation of hepatic lipogenic enzymes and favoring increased hepatic lipogenesis [56,57,58]

In the era of multiple biomarker development, panels of biomarkers, including GST, should be validated for additional value in combining more than one biomarker

Baseline characteristics were compared using Fishers Exact test for categorical variables and linear mixed effect models for continuous variables

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