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Unlike FDA-approved Wegovy, which has undergone rigorous clinical trials and quality control measures, compounded semaglutide lacks regulatory oversight and standardization in its formulation

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Of note, the dopamine neurons in the ARH also regulate pituitary hormones (71), which could be linked to the GLP-1 stimulatory release of pituitary hormones, such as vasopressin and corticotropin-releasing hormone (72)