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543 The JAK-STAT pathway serves as a hub for cytokine signaling, and inhibitors such as tofacitinib effectively block IL-6- and IL-23-mediated immune cell activation by competitively occupying the ATP binding site of the kinase

10.1016/S0306-4522(00)00293-1 Neuroscience 100 RodriguezM.MoralesI.Rodriguez-SabateC.SanchezA.CastroR.BritoJ