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In the current clinical scenario, Tirzepatide, a dual agonist of glucagon like peptide 1 and glucose dependent insulinotropic polypeptide receptors, has been shown to reduce the apnea hypopnea index by up to nearly two thirds in patients with obesity

doi: 10.2174/0115734072286081240326082701 79 YiY-S

However, safety depends on several factors: injection site rotation to avoid lipodystrophy, adequate hydration (both agents can increase fluid demand), and monitoring of B vitamin status since semaglutide may affect nutrient absorption slightly during rapid weight loss phases

Clin Nutr 2012;31(2):176-182