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MRM data were analyzed using Skyline software (version 20.0, University of Washington) to quantify metabolites for flux analysis

Sublethal mitochondrial stress with an attendant stoichiometric augmentation of reactive oxygen species may precipitate many of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients: mitohormesis for health and vitality

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