69 In comparison, newer oral small-molecule GLP-1 RAs, such as danuglipron and orforglipron, have demonstrated similar efficacy
However, the FDA has expressed concerns about their use as they do not meet the Federal Food, Drug, and Cosmetic Act requirements for compounding
Robert Darling, Chief Medical Officer, Get Thin MD Here's Why NAD+ Injections Are Essential for Your GLP-1 Journey +ENHANCED ENERGY AND VITALITY While GLP-1s help control your appetite, NAD+ injections provide the cellular energy you need: Directly supports mitochondrial function your cells' power plants Combats the fatigue commonly associated with reduced calorie intake Provides sustained, natural energy without stimulants Helps maintain energy levels throughout the day Supports motivation for physical activity despite eating less +OPTIMIZED METABOLISM AND FAT BURNING Getting the most from your GLP-1 journey means supporting your metabolism: Helps prevent metabolic slowdown during weight loss Supports efficient fat oxidation and utilization Enhances thermogenesis (calorie-burning heat production) Promotes insulin sensitivity in muscle tissue Helps overcome frustrating weight loss plateaus +MUSCLE PRESERVATION AND BODY COMPOSITION Lose fat, not muscle, with NAD+ support: Facilitates muscle energy production during workout recovery Supports protein synthesis and muscle maintenance Enhances physical performance during exercise Promotes ideal body composition changes Helps prevent the loss of lean mass during rapid weight loss The Science Behind NAD+ for GLP-1 Users NAD+ (nicotinamide adenine dinucleotide) is often called the "molecule of life" a critical coenzyme found in every cell of your body that powers metabolism, cellular repair, and energy production
Symptoms of folate deficiency Some of the symptoms that can be caused by a lack of folate include: General symptoms Fatigue Irritability Headache Dizziness Gastrointestinal symptoms Sore tongue Mouth ulcers Diarrhea Loss of appetite Neurological symptoms Numbness and tingling in the hands and feet Confusion Depression Cognitive impairment Dementia Hematological symptoms Anemia (pale skin, shortness of breath) Testing for vitamin B12 and folate deficiency When to test Since vitamin B12 and folate affect many functions in the body and there are many possible symptoms, blood testing for vitamin B12 and folate is commonly ordered by the physicians at the Adult Down Syndrome Center
Exploring the underlying mechanisms, Dong et al
Results Uridine enhances fertility and oocyte maturation competence in aged mice Metabolic dysregulation can induce ovarian dysfunction and consequently accelerate the decline of female fertility 24
