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doi: 10.1074/jbc.RA119.010949 42 SwaminathanS

While three forms of cystinosis have been described, the disorder displays a continuum of clinical severity inversely related to the amount of residual cystine-transporting activity

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J.LiewS

Buzio, L

8, 9, 10, 11, 12 these patients and experimental animals have a diminished antioxidant status, 13 which contributes to the accumulating evidence that increased vascular oxidative stress could be involved in the pathogenesis of essential hypertension