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Follow your doctors guidelines, which will typically start with the lowest recommended dose of semaglutide and increase it gradually over time

If its been more than five days since your missed dose, skip that dose altogether and take your next dose as scheduled on your normal injection day

Tirzepatide is a dual GLP-1 and GIP agonist that activates two hormone pathways, producing greater weight loss than semaglutide

The combination is a real dehydration risk, particularly for tirzepatide users where dehydration from GI side effects has been associated with kidney complications

The CDC also warns that some people may eat too much because they do not feel the effects right away

Others may prefer to reach the maximum dosage as fast as possible so they can enjoy optimal weight loss benefits