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In summary, CDC42, derived from neural stem cell-derived exosomes, as well as TIGAR, FTO, and IRP2, contribute to PD pathology by regulating iron homeostasis, ferroptosis, fatty acid metabolism, the antioxidant system, and angiogenesis

Vitamin D deficiency is a major problem worldwide, with an estimated one billion people having insufficient or deficient levels of circulating 25-hydroxyvitamin D (48)

Impact of Smoking and Alcohol Consumption on Oxidative Status in Male Infertility and Sperm Quality

W.SatyamurthyN.KepeV.BarrioJ

Stewart, E

The Gpx family of glutathione peroxidases is an evolutionarily highly conserved group of enzymes containing eight main isoenzymes, among which Glutathione Peroxidase 4(GPx4) utilizes GSH as a cofactor to convert lipid hydroperoxides into nontoxic lipids alcohols and reduce free radical accumulation (36)