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By integrating these disparate elements, our work emphasises the necessity of a holistic approach to diagnosing, researching, and treating ME/CFS, urging the scientific community to reconsider the diseases complexity and the multifaceted approach required for its study and management

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More recently, a breakthrough 2026 study utilizing both in-vitro cellular models and an in-vivo human pharmacokinetic trial further solidified these findings

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Too much signal and you waste money without additional benefit, the response curve plateaus rather than climbing indefinitely