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This finding is reminiscent of our previous observations of the robustness of cytosolic glutathione redox homoeostasis, which largely relies on continuous NADPH supply, indicating that the robustness in NADP redox state also serves the stability of downstream redox pools 21

22 French Maritime Pine Bark A standardized extract from French maritime pine bark known as Pycnogenol was tested for its effects in an open clinical trial that included 64 participants with recurrent urinary tract infections or interstitial cystitis

[DOI] [PubMed] [Google Scholar] (602).Jiang B

However, elucidation of the factors that underlie the sensitivity of a given cell type to ferroptosis7 is crucial to understand the pathophysiological role of ferroptosis and how it may be exploited for the treatment of cancer