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Monitoring of vitamin B12 replacement Most people who start vitamin B12 replacement notice an improvement in symptoms within 2 weeks, although they may take several months to resolve completely

Subjective improvements in energy or mood are often felt within days to a few weeks after an injection when deficiency is present

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Based on evidence from clinical studies, the USPHS, AAP, and ACOG recommend a folic acid intake of 0.4 mg/day PO from food and/or supplements in females during the child-bearing years, and 0.6 mg PO daily throughout pregnancy