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However, as age increases, the balance between ROS production and antioxidant defenses deteriorates, leading to chronic oxidative stress across organ systems

doi: 10.2174/187152011795677544

they frequently lack appropriate specificity, chemical stability, or interference resistance to cellular components [115] and they are mostly incapable of simultaneously quantifying the intricate network of interconnected redox couples (e.g., GSH/GSSG, NAD/NADH, and Trx redox states) with adequate sensitivity under physiologically relevant conditions [116]

Additionally, it may ameliorate side effects related to antipsychotic medications, such as akathisia and metabolic disturbances, thus improving patient adherence and overall quality of life (227,231)

Natl Vital Stat Rep 58:1132 Charache S, Barton FB, Moore RD, Terrin ML, Steinberg MH, Dover GJ, Ballas SK, McMahon RP, Castro O, Orringer EP (1996) Hydroxyurea and sickle cell anemia

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