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Repeat injections require documented improvement from prior injections, and sessions beyond four require a clinical appeal with the MAC

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The best non-diabetic body-composition anchor favors tirzepatide, about 75:25 fat-to-lean loss in its DXA data versus about 62:38 in semaglutides. This is cross-trial evidence, not a head-to-head maintenance-dose DXA result

it has been used topically for decades without serious adverse events, and injectable formulations in animal models show no organ toxicity at doses up to 50 mg/kg" [8]

Does not diagnose or treat disease

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