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PMID: 199 Lo ConteMCosorichIFerrareseRCencicchioMANobiliAPalmieriVet al

far more potent in preclinical work

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Bagga P, Hariharan H, Wilson NE, et al

It is the primary substrate for the body's antioxidant defense network directly quenching reactive oxygen species that damage DNA, proteins, and cellular membranes

These studies indicate that overproduction of glutathione drives the survival and growth of a small subset of lymphoid tumor cells in 3D gels and xenografts, likely TIC or TIC-like cells, and that glutathione is selectively required for tumor growth in females of a mouse model of lymphoma

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