Always helpful when I have a question
Regardless, the absence of reported side effects doesnt eliminate the need for caution
Same day is simpler, but some users split them - tirzepatide Monday and cagrilintide Thursday - to spread out GI side effects during titration
Escalation: Step the dose up every few weeks e.g
Several factors can impair B12 absorption: Reduced stomach acid production (achlorhydria or hypochlorhydria), common in older adults and those taking proton pump inhibitors or H2-receptor antagonists long-term, impairs the release of B12 from food proteins Pernicious anaemia , an autoimmune condition destroying parietal cells and reducing intrinsic factor production, completely blocks the primary absorption pathway Gastrointestinal disorders including Crohn's disease, coeliac disease, or surgical removal of stomach or ileum sections directly damage absorption sites Metformin , commonly prescribed for type 2 diabetes, may reduce B12 absorption through unclear mechanisms
In some women, the effects of alcohol tend to be stronger and last longer
