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Tirzepatide is a dual-receptor medication: it works on both the GLP-1 and GIP pathways, which are involved in digestion, fullness signaling, and how the body handles energy

The other currently available once-weekly GLP-1 agonists in the US Astra Zenecas Bydureon (exenatide) and GSKs Tanzeum (albiglutide) require a reconstitution process that takes time to prepare before use

Surgery is for people who have struggled to lose weight with other treatment methods

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, 533 , 1034-1038, Yamamoto, J., Inubushi, S., Han, Q., Tashiro, Y., Sugisawa, N., Hamada, K., Aoki, Y., Miyake, K., Matsuyama, R., Bouvet, M., Clarke, S