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Initial trials of semaglutide in pregnant rats showed an increase in pregnancy loss, birth defects and low birth weight 8

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Semaglutide slows stomach emptying, and coffee can worsen nausea or reflux symptoms in some patients

Furthermore, in vivo models suggest that intratesticular or peritesticular injections of PRP may promote spermatogenesis, restore testicular architecture, and mitigate damage caused by toxins, ischemiareperfusion injury, or diabetes-induced degeneration [35,36,37,38]

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Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7): a randomised, open-label, phase 3b trial