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Mucosal Immunol 10:15531568 Matarrese P, Straface E, Pietraforte D et al (2005) Peroxynitrite induces senescence and apoptosis of red blood cells through the activation of aspartyl and cysteinyl proteases

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Vitamin B12 deficiency symptoms: 'Tingling' skin might be a warning sign to see your GP A VITAMIN B12 deficiency will cause abnormally large red blood cells to form, meaning oxygen - a life-sustaining molecule - can't sufficiently be transported around the body

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