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While recent research indicates ipamorelin is typically non-harmful, extended use could potentially impact reproductive hormones

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Head-to-head phase 3 trials comparing icotrokinra against deucravacitinib and placebo [ICONIC-ADVANCE 1 (NCT06143878) and ICONIC-ADVANCE 2 (NCT06220604)] in adults with moderate-to-severe plaque psoriasis are ongoing

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In the NHS, access to Wegovy is governed by NICE Technology Appraisal 875, which specifies additional eligibility criteria beyond the licensed indications