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Clinical takeaways Our biological framework proposes a potential mechanism by which serotonergic circuitry may underlie an association between GLP-1 agonist medications and a decrease in sexual desire

Muscle Weakness Low glutathione can lead to muscle weakness and greater fatigue during workouts

Metoclopramide carries an FDA boxed warning for tardive dyskinesia and should be used for the shortest duration possible, typically less than 12 weeks

In the CFA-induced chronic inflammatory pain model, mice with CFA-induced inflammation presented prolonged heat hyperalgesia following intraplantar vehicle administration

More serious, but rare, side effects can include pancreatitis, gallbladder problems, and allergic reactions