New @NEJM review on GLP-1 receptor agonists just out: effects on glucose, weight, cardiovascular outcomes, #MASLD and kidney outcomes but important questions remain about durability, lean mass (muscle + bone) loss, and long-term safety
Seek medical advice if you experience severe or persistent abdominal pain (especially radiating to your back), blood in vomit or stools, persistent vomiting, signs of dehydration, jaundice, or symptoms that worsen despite treatment, as these may indicate serious complications
50% of Gen Z and 40% of millennials have fewer or less painful periods when using GLP-1s
It has also been reported that liraglutide increases neural stem cell proliferation and neuronal differentiation in the APP/PS1 neurodegenerative disease model (Parthsarathy and Holscher, 2013a)
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Lemieux, G
