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In animal models of heart failure induced by high-frequency pacing, ischaemia, and obesity, GLP-1RAs inhibit left ventricular remodelling and improve left ventricular contractility and diastolic function through anti-inflammatory effects, cardiomyocyte apoptosis inhibition, and glucose metabolism enhancement in cardiomyocytes [38,39,40]

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Exenatide works more quickly but with similar benefits

Curcumin Action: Intestinal anti-inflammatory more active L cells more GLP-1 Dosage: 500-1000 mg/day (liposomal form = 30 absorption) 3

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