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In a 48-week phase 2 trial published in The New England Journal of Medicine , adults with obesity (without type 2 diabetes) receiving once-weekly subcutaneous retatrutide at the 12 mg amount achieved a least-squares mean body weight reduction of 24.2%, compared with 2.1% in the placebo group [1]

Good news, Schacht said

Victoza uses liraglutide , while Ozempic leverages semaglutide, a more effective compound requiring fewer injections (weekly vs

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doi: 10.1016/j.pharmthera.2022.108277 102 WangLZhaiY-QXuL-LQiaoCSunXLDingJHet al

These injections last just under a week, so it is recommended to receive the injections twice a week, and include a Vitamin B12 shot for maximum benefit