GLP-1s are great for patients, but I have a huge reluctance to see these third-party vendors managing this disease because they have limited expertise, and they're using experiment and not data to treat their clients, she says
When Wegovy is covered, it almost always sits in the non-preferred tier with strict prior authorization requirements
Several options can make these drugs more affordable
Tirzepatide Semaglutide (Ozempic/Wegovy) activates GLP-1 receptors, which: Slows stomach emptying Reduces appetite Improves insulin sensitivity Typically results in 15-20% weight loss over a year Tirzepatide (Mounjaro/Zepbound) activates both GLP-1 and GIP receptors, which: Provides all semaglutide benefits May have stronger effects on glucose metabolism Often results in 20-25% weight loss over a year Sometimes has fewer gastrointestinal side effects Your optimal choice depends on your specific PCOS presentation
Once-weekly formulations such as semaglutide (Ozempic, Wegovy) and dulaglutide (Trulicity) can be administered at any time of day, with or without meals, according to their SmPCs
Significant weight reduction was seen, but bone mineral density (BMD) did not change
