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Nrf2 upregulates the expression and activity of SLC7A11 in breast cancer cells during oxidative stress, and promotes the survival of breast cancer cells from drugs and other treatments by antagonizing ROS, while Nrf2 expression is downregulated when ROS levels are reduced (Habib et al., 2015

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The statements that are not supported by evidence are broad: any claim of proven human benefit, any specific human dose or half-life presented as established, any therapeutic indication, and any assertion that preclinical muscle findings translate to human outcomes

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