1 Introduction Breast cancer remains a significant public health problem because to its high incidence, extensive morbidity, or fatality rates, and the fact that it is the most frequent cancer in women worldwide, even though screening and therapy have made advances ( Factors such as increased life expectancy, more urbanisation, different lifestyle choices, and eventual reproductive ages are contributing to the diseases increasing prevalence, particularly in countries with low or middle incomes (LMICs) ( The upsurge of interest on natural supplements such as phytochemicals, plant extracts, and bioactive components (namely vitamins, minerals, polyphenols, flavonoids and nutraceuticals) for their potential anticarcinogenic, antioxidant, anti-inflammatory as well as immune-modulatory effects over and above conventional breast cancer management has been observed in response to the aforementioned clinical challenge
Genetic background influences bone loss in PMO by affecting the GM, establishing baseline bone mass, regulating the distribution of antigen-presenting cells (APCs), and influencing the development and activity of the host immune system
187 Dehydroepiandrosterone (DHEA) Dehydroepiandrosterone (DHEA) is a hormone produced mainly in the adrenal cortex, with smaller amounts produced in the testes, ovaries, and brain
3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance
The comparative anti-oxidant and anti-inflammatory efficacy of postbiotics and probiotics through Nrf-2 and NF-kB pathways in DSS-induced colitis model
Tang LJ, Luo XJ, Tu H, Chen H, Xiong XM, Li NS, et al
