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In juvenile rat hippocampal slices, pyruvate administration was able to restore ATP levels and rescue neurons against NMDA mediated excitotoxicity (Izumi and Zorumski, 2010)

Gubatan J, Keyashian K, Rubin SJS, Wang J, Buckman CA, Sinha S

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The applicator delivers the same peptide as the lyophilisate vial, but in the form of a ready solution with two main consequences for laboratory work

When combined with lipid-based nanoparticles, the ISG system creates a synergistic effect, further enhancing the overall effectiveness of brain-targeted delivery strategies

These benefits persisted after adjusting for multiple potential confounders including baseline liver disease severity, comorbidities, and use of other medications [55]