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Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma

doi: 10.4155/fmc-2018-0436 43

In WT cells, both OPTN and NDP52 formed cup-shaped and/or sphere-like structures on damaged mitochondria (Fig 1j) that were previously reported to co-localize with LC3B-labeled autophagic membranes 49, 56, 69