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Description

At a systemic level, semaglutide significantly reduced circulating levels of numerous inflammatory and pro-fibrotic proteins, including master regulators of fibrosis such as IL-11 which is the dominant transcriptional response to TGF1 exposure and required for its pro-fibrotic effect 63

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Gaayn-Sidorczuk et al., 2012)

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ORO extraction and calorimetric estimation All steps of the ORO staining protocol were carefully followed up until the first wash with PBS after the ORO staining step

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