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Approximately 86% of patients with T2DM are overweight or obese, and obesity is considered the greatest risk factor for T2DM (Daousi et al., 2006

This upregulation of hepatic DPP4 expression is thought to be responsible for elevated DPP4 serum level in patients with liver disease (153155)

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This toxic metabolite can bind covalently to proteins and cause cell necrosis

A peer-reviewed review in Frontiers in Endocrinology summarizing the mechanisms and clinical potential of peptide-based interventions for obesity and metabolic dysregulation provides the scientific foundation that positions Tesamorelin and similar peptides as credible tools in weight management beyond the GLP-1 paradigm

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