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Chiara Di Loreto declared to receive: an honoraria for advisory board membership from Novo Nordisk and Lilly, consulting fees from Novo Nordisk

Retrieved 28 June 2026

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It is not: A proven life-extension therapy A cure for cognitive decline A substitute for foundational health behaviors Appropriate for everyone It appears most beneficial for: High-functioning adults experiencing age-related metabolic or cognitive decline Patients with documented NAD+ depletion or methylation dysfunction Individuals who've optimized lifestyle factors and are seeking targeted cellular support Those willing to invest in multi-session protocols with proper medical oversight The evidence base will continue to evolve