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Prior to widespread implementation of the Haemophilus influenzae type b (Hib)-conjugate vaccination programs in the 1990s, Hib was the most common cause of bacterial meningitis in children under the age of five (Heath et al., 2001

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The lack of OCTN2 can determine high renal loss of carnitine, lower concentrations of carnitine in blood and tissues, and decreased intracellular carnitine accumulation [58,74]

It provides actionable evidence that if the goal is durable neural remodeling and mTOR suppression, continuous intranasal administration is vastly superior to sporadic systemic injections

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