A 2021 review confirmed no clinical trials targeting NNMT had been reported [5], and MOTS-c likewise has no large human efficacy trial proving it works as a fat-loss therapy
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4.2 Imaging 4.2.1 Introduction to imaging techniques for ferroptosis detection Studies combining imaging techniques such as MRI and magnetic nanoparticles for in vivo ferroptosis observation initially emerged in oncology research, where ferroptosis modulation represents a novel treatment approach that potentially overcomes resistance to conventional cancer therapies
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Techniques for cellular activities MTT colorimetric assay The MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (Sigma, MO, USA) assay was employed to evaluate the cytotoxicity and cell viability induced by the targeted compounds
doi: 10.1038/s41564-018-0337-x 101 BoQTianLLiFMaoZWangZMaXet al
