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May 2020;32(5):601-608

Chronic Complication Mechanisms: Sustained hyperglycemia damages small vessels (microvascular disease) via multiple mechanisms including AGE accumulation, protein kinase C activation, and hexosamine pathway flux

In contrast with older agents that carried risks of weight gain or hypoglycemia, todays drugs provide protective benefits that extend far beyond glycemic control

Consequently, they are well-suited for integration with conventional Western treatments to provide safer and more effective management of thyroid diseases (Zhang et al

The angiotensin IV analog Nle-Tyr-Leu--(CH 2 -NH 2 ) 3-4 -His-Pro-Phe (Norleual) can act as a hepatocyte growth factor/c-Met inhibitor

DOI: 10.1002/cbdv.201400415 58