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3.2 Lactic acidosis During metformin treatment, plasma lactate concentration increases with enhanced glucose uptake in the intestine, resulting in side effects in some patients with one or more risk factors for lactic acidosis (Bailey et al., 1992

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Insulin resistance in type 1 diabetes Insulin resistance is associated with micro- and macrovascular complications in patients with T1D (28)

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Lipotropic injections carry additional safety concerns due to their unregulated nature and variable composition